| CONCENTRATED FLAX HULL LIGNANS: |
FLAX LIGNANS (SDG) Flax Hulls Linum usitatissimum- We can offer beautiful quality concentrated flax hull lignans, containing large concentrations of Lignans (SDG). Lignans are a group of phytonutrients found in seeds and grains. Flaxseed is known for being the plant containing the highest concentration of Lignans known as SDG (secoisolariciresinol diglycoside) |
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Flax Information:
Most of the lignans in the flax seed are located in the hull that encased
the seed. Our product contains only pure organic flax hulls, which
have been mechanically separated from the flax seed. The resulting
product is said to contain 70 times the amount of SDG lignans per gram as
compared to the traditional ground up seed.
Studies have shown these SDG
lignans to be effective in a variety of health complications. Much
extensive study has been done on the effects of flax lignans on
certain diseases such as Prostate cancer, Skin cancer, Melanoma, Diabetes,
Lupus and many more.
Being Phytoestrogens, SDG
lignans have also been reported to be effective in balancing hormone
related problems in women. These have included breast tenderness,
sweating, vaginal dryness, bloating, hot flashes and uneven menstrual
cycles and PMS symptoms.
ANALYSIS OF
CONCENTRATED FLAX HULL LIGNANS
Test
Results
Units
Moisture- Forced Draft
Oven..........................................9.30 %
Protein -
Combustion...................................................24.96
%
Ash................................................................................4.89
%
Fiber, Acid
Detergent.................................................... .18.1 %
Lignan...........................................................................30-65 %
Fiber, Dietary,
Total........................................................51.5
%
Carbohydrates,
Calculated..............................................52.64 %
Calories.............................................................................384
Calories/100 G
Tryptophan........................................................................0.24
%
Cystine...............................................................................0.41
%
Methionine..........................................................................0.42
%
Aspartic
Acid......................................................................2.28 %
Theonine.............................................................................0.93
%
Serine..................................................................................1.15
%
Glutamic
Acid......................................................................4.32
%
Proline.................................................................................0.84 %
Glycine................................................................................1.39
%
Alanine.................................................................................1.05 %
Valine...................................................................................1.10 %
Isoleucine.............................................................................0.90
%
Leucine.................................................................................1.31
%
Tyrosine................................................................................0.47
%
Phenylalanine..........................................................................1.02
%
Lysine,
Total..........................................................................0.88
%
Histidine.................................................................................0.48
%
Lignin.......................................................................................7.0
%
Arginine...................................................................................1.88 %
Total
Fat..................................................................................8.21*
%
Saturated Fatty
Acid..................................................................0.76**
%
*Reported as triglycerides **Reported as fatty acids
Total Monounsat. Fatty
Acids Calc.............................................1.30
%
Total Polyunsat. Fatty
Acid Calc.................................................5.79
%
Calcium.....................................................................................0.48 %
Phosphorus................................................................................0.58 %
Iron...........................................................................................0.010
%
Magnesium..................................................................................0.43
%
Potassium....................................................................................1.06 %
Sodium........................................................................................0.042 %
Zinc..........................................................................................0.0055 %
Niacin...........................................................................................34.4 MG/LB
Vitamin B1 - Thiamine
Hydrochloride.............................................7.12 MG/LB
Vitamin B2 -
Riboflavin...................................................................2.69
MG/LB
(analysis done by Woodson-Tenent Laboratories www.wtlabs.com)
Microbial
Analysis for Concentrated Flax Hull Lignans
Aerobic Plate Count .............................................................50CFU/g
Yeast and Mold
Count..........................................................30 CFU/g
Coliform
Count.....................................................................None
detected
E.coli
Count..........................................................................None
detected
Salmonella spp.(+/-)..............................................................Negative
(Microbial analysis
done by department of veterinary & microbiological science
NDSU at fargo)
SDG Lignans Information:
Reactive
oxygen species (ROS) have been implicated in the development of diabetes
mellitus. SDG isolated from
flaxseed is an antioxidant. An
investigation was made of the effects of SDG on the development of
diabetes in rats, to determine if SDG can prevent/reduce the development
of diabetes and if this prevention/reduction is associated with reduction
in oxidative stress. RESULTS: SDG prevented the
development of diabetes by
75%. (Prasad K, et a, Mol Cell Biochem, 206(1-2): 2000; Prasad K. Mol Cell Biochem, 209(1-2): 89.2000)
Flaxseed
SDG may have a therapeutic role in
lupus nephritis. (
Clark
W. et al Lupus, 9(6): 429, 2000)
Asian
men have a much lower incidence of prostrate cancer and possibly of benign
prostatic hyperplasia (BPH) than Western counterparts. Vegetarian men have a lower incidence of prostate cancer than
omnivorous males. Plant lignans give rise to the mammalian lignans,
enterodiol and enterolactone; the richest source is linseed (flaxseed). In addition to their oestrogenic activity, these plant compounds
can interfere with steroid metabolism and bioavailability, and also
inhibit enzymes, such as tyrosine kinase and topoisomerase, which are
crucial to cellular proliferation and hence may contribute to lower
incidences of prostrate cancer. (Eur
Urol, 35(5-6): 377, 1999)
Dietary
estrogens, such as lignan-rich flaxseed, are similar in structure to
endogenous sex steroid hormones and act in vivo to alter hormone
metabolism and reduce subsequent cancer risk in postmenopausal women.
(Hutchins A, Cancer Epidemiol Biomarkers Prev, 9(10): 1113, 2000)
Research
suggests that SDG reduces hypercholesterolemic atherosclerosis and that
this effect is associated with a decrease in serum cholesterol, LDL-C, and
lipid peroxidation product and an increase in HDL-C and antioxidant
reserve. (Prasad K.
Circulation, 99(10): 1355, 1999)
Phytoestrogens
are diphenolic compounds that are present in several plants eaten by human
beings. Flaxseed is a
particularly abundant source of phytoestrogens. When ingested in relatively large amounts, phytoestrogens have been
shown to have significant estrogen agonists/antagonists effects in animals
and humans. There is
epidemiological, laboratory and clinical evidence which indicates that
phytoestrogens, like certain selective estrogen receptor modulators, have
an antiproliferative effect on the breast, and positive effects on the
lipoprotein profile and bone density. They might also improve some of the climacteric symptoms. (Brzezinski A & Bebi A. Eur J Obstet Gynecol Reprod Biol.
85(1): 47, 1999.
Flaxseed
is high in secoisolariciresinol diglycoside (SDG), the precursor of
mammalian lignans, which can affect mammary gland structure. Lifetime or gestation and lactation exposure to 5 or 10% flaxseed
induce structural changes in the mammary gland that may potentially reduce
mammary cancer risk. (Tou J
& Thompson L. Carcinogenesis, 20(9): 1831, 1999)
Flaxseed
and SDG, regardless of dose, appeared to delay the progression of MNU-induced
mammary tumorigenesis. (Rickard
S. et al, Nutr Cancer; 35(1): 50, 1999)
Because
flaxseed and its lignans are colon cancer protective, it is concluded
that, in contrast to other studies, beta-glucuronidase activity may play a
beneficial role in their presence by increasing mammalian lignan
absorption and enterohepatic, (Jenab M, et al, Nutr Cancer, 33(2): 154,
1999)
Dietary
supplementation with secoisolariciresinol diglycoside (SDG), a lignan
precursor isolated from flaxseed, significantly reduced pulmonary
metastasis cells and inhibited the growth of metastatic tumors that formed
in the lungs. (Li D. et al, Cancer Lett, 142(1): 91, 1999)
Flaxseed
the richest source of lignans reduces metastasis and inhibits the growth
of the metastatic secondary tumors in animals. Flaxseed may be a useful nutritional adjuvant to prevent melanoma
metastasis in cancer patients. (Yan L, et al, Cancer Lett, 124(2): 181,
1998)
Flaxseed
contains lignans that have antioxidant activities and inhibit
platelet-activating factor (PAF). Pretreatment
with flaxseed attenuated emdotoxin induced cardiac dysfunction and
cellular damage. Flaxseed
antioxidant and anti-PAF agents may be effective in the treatment of ET
shock. (Pattanaik U & Prasad K, J Cardiovasc Pharmacol Ther, 3(4):
305. 1998)
The
mammalian lignans enterolactone (EL) and enterodiol (ED) derived from
precursors in foods, particularly flaxseed, have been shown to reduce the
mammary tumor growth due to their antiestrogenic properties. Lignans are
growth inhibitors of colon tumor cells and they may act through mechanism(s) other than antiestrogenic
activity, (Sung M, et al, Anticancer Res 18(3A: 1405, 1998)
Flaxseed,
the richest source of mammalian lignan precursors, such as
secoisolariciresinol diglycoside (SD), has been shown over the short term
to decrease some early markers of colon cancer risk. This study determined that flaxseed has a colon cancer protective
effect, that it is due, in part to SD and that the protective effects of
flaxseed is associated with increase beta-glucuronidase activity. (Jenab M
& Thompson L, Carcinogenesis, 17:1343, 1996)
Flaxseed,
a rich source of mammalian lignan precursor
secoisolariciresinol-diglycoside _SD) and alpha-linolenic acid (
ALA
), has been shown to be protective at the early promotion stage of
carcinogensis. In conclusion, the SD lignans in flaxseed appears to be
beneficial throughout the promotional phase of carcinogenesis whereas the
oil components is more effective at the stage when tumors have already
been established. (Thompson L, et al, Carcinogenesis, 17:1373, 1996)
Flaxseed
lignans have antitumor, antimitotic, antioxidant and weak estrogenic
activity, are potentially the richest source of phytoestrogens in the
human diet and may be linked to a low incidence of breast and colon
cancer. Secoisolariciresinol
was discovered to be a very potent antioxidant similar to BHA. No toxicity was found in the lignans. (Obermeyer W, et al (US Food and Drug Administration, center for
Food Safety and Applied Nutrition, Div. Contaminants Chem., Natural
Products Branch), Meeting Of The Federation Of American Societies For
Experimental Biology On Experimental Biology March/April, 1993, Faseb J
(Fed Am Soc Exp Biol), A863, 1993)
Vitamin
E-deficient diets containing 5 to 20% ground flaxseed protected mice
against the malarial parasite Plasmodium voelii as shown by decreased
parasitemia and enhanced survival. (Levander O, et al, (USDA/ARS Human
Nutrition Research Center, Vitamin Mineral Nutrition Laboratory),
Nutrition Research, 11, 1991)